IGF-1, or insulin-like growth factor 1, is a naturally occurring protein hormone that stimulates growth and plays a role in muscle development, bone density, and overall health. It has important insulin-like metabolic effects in adults. IGF-1 is mainly produced in the liver under stimulation by growth hormone (GH).
When GH is secreted from the pituitary gland, it circulates to the liver and triggers IGF-1 production and release into the bloodstream. This is the primary method by which growth hormone exerts its anabolic effects on the body. GH serves to “turn on” IGF-1 activity.
How To Use IGF-1?
Pharmaceutical IGF-1 comes in injectable form only, as the protein would be broken down if given orally. For muscle building, injury recovery, and anti-aging, IGF-1 is injected subcutaneously, just under the top layer of skin.
Common injection sites include the abdomen, thighs, and upper arms. Rotating sites is recommended to avoid irritation or the buildup of scar tissue. IGF-1 doses are measured using an insulin syringe or pen injector.
Most users will inject IGF-1 once or twice per day, with one dose usually being given post-workout when muscles are primed for growth. However, some users report dividing the dosage into three injections taken before meals. IGF-1 should not be dosed too close to workouts to avoid potential hypoglycemia.
What are the Benefits of IGF-1?
Clinical research and anecdotal reports suggest that potential IGF-1 benefits include:
- Increased lean muscle mass: By boosting protein synthesis and nitrogen retention, IGF-1 can lead to significant muscle hypertrophy when combined with proper training and nutrition.
- Accelerated muscle injury recovery: IGF-1 speeds the repair of muscle tears and damage induced by exercise. This allows for faster gains by enabling more frequent, intense workouts.
- Enhanced strength gains: higher circulating IGF-1 amplifies neurological signaling that can lead to improved muscle strength and power output.
- Reduced body fat: IGF-1 increases lipolysis and fat metabolism, even in cases of GH resistance. Less fat storage occurs as well.
Are there Side Effects of IGF-1?
When used responsibly under medical supervision, IGF-1 has a relatively mild side-effect profile. However, potential adverse effects may include:
- Hypoglycemia: IGF-1 can lower blood glucose by enhancing uptake into cells. Eating carbohydrates in small doses largely prevents this effect.
- Water retention: fluid retention is possible due to IGF-1’s influence on renal physiology. Adequate hydration reduces this side effect.
- Numbness or tingling: Some users report these neuropathy symptoms. Reducing dosage often alleviates this.
- Headaches: Sporadic headaches may occur. Taking doses with food seems to minimize headaches for most people.
- Joint pain: There are claims of occasional joint discomfort or pain with IGF-1 use. Proper cycling can reduce this occurrence.
For physique enhancement purposes, typical IGF-1 dosage protocols are:
- Beginner dose: 20–40 mcg per day
- Common dose: 50–80 mcg per day
- Advanced dose: up to 150 mcg per day (higher doses may increase side effects)
Start at lower dosage ranges and assess tolerance before increasing. Given its relatively short half-life, split the total dosage into at least two injections per day: one pre-workout and one post-workout, or before bed. Use IGF-1 for 4-6-week cycles and take the same amount of time off in between cycles. Never exceed 150 mcg daily without medical guidance.
Where to buy online IGF-1?
IGF-1 can be purchased through licensed sources that manufacture peptides under cGMP guidelines. Reputable companies test their peptides for purity and dosing accuracy. Do extensive research before buying peptides from BuyPeptidesusa products. Confirm they provide third-party assay reports to validate quality. With due diligence, pharmaceutical-grade IGF-1 can be sourced online safely and legally.