Placeholder

Hexarelin 5mg

£27.99

Buy Hexarelin Online Today at Enhanced Peptides. Fast Shipping from the USA. Over 100 High Quality Peptides and Research Chemicals for sale.

SKU: Hexarelin 5mg Category:

Hexarelin (Examorelin)

Also known as Hexarelin Peptide, Examorelin

Derived from GHRP-6, Hexarelin is considered a synthetic growth hormone secretagogue with similar effects as ghrelin. Otherwise known as Examorelin, its function includes promoting the development of lean body mass, and boost plasma levels of growth hormone.

Also, secondary functions of hexarelin include; reduction of lipid levels, improving cardiac function, and protection against adverse effects of some specific chemotherapeutic. Recent studies are being done to see the impact of it on metabolic diseases like diabetes.

 

Chemical Description

Chemical Structure:

Hexarelin Acetate Chemical Structure

Molecular Formula: C47H58N12O6

Molecular Mass: 887.04022

Amino Acid Sequence: His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys

 

Research Applications

Recent studies are being done to see the effect of hexarelin on metabolic diseases like diabetes. The peptide has been observed to activate CD36-PPARy. The PPARs are a frequent target of most pharmaceuticals that want to enhance insulin resistance.   An increase in insulin resistance will help maintain lipid metabolism along with reducing blood sugar levels in type 2 diabetes.

Studies are also carried out on the effect of this peptide as a cardiac protective agent. The peptide has the ability to inhibit scar formation after a heart attack, inhibit atherosclerotic plaques formation, and offer protection of heart muscle after a heart attack. In a study carried out on mice with cardiac ischemia, it was observed that there was an improvement in different cardiac parameters after 2 weeks following the injection.

 

What is Hexarelin?

Derived from GHRP-6, Hexarelin is considered a synthetic growth hormone secretagogue with similar effects as ghrelin.  It’s structure is His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys. It is very similar to GHRP-6 in terms of structure with the only difference in the methyl-tryptophan bond in the second position.

 

Roles

Hexarelin doesn’t produce any significant changes in prolactin or cortisol, neither does it have any substantial effect on glucose levels, thyroid stimulating hormone, or luteinixing hormone.
On the other hand, it enhances an increase in growth hormone similar to the role GHRP-6 does.

 

Metabolic research

Emphasis on metabolic research on Hexarelin is placed on lipid metabolism and insulin resistance. In an experiment carried out on rats, it was shown to boost insulin resistance in diabetic rats via the activation of beta cells of the pancreas and PPARY. Studies show that along with improving the function of existing beta cells, it also helps in the regeneration and recovery of beta cells in the pancreas.

In regards to lipid metabolism, it has shown its ability to improve plasma glucose levels, and this helps to lower the risk of diabetes and also limit insulin secretion from the pancreas in a study done on non-obese mice with irregular metabolism.

 

Cardiac Research

Hexarelin has enormous potential in offering cardioprotective benefits most especially in situations involving cardiac injury. The peptide has the ability to inhibit scar formation after a heart attack, inhibit atherosclerotic plaques formation, and offer protection of heart muscle after a heart attack. In a study carried out on mice with cardiac ischemia, it was observed that there was an improvement in different cardiac parameters after 2 weeks following the injection of hexarelin. It can also limit apoptosis resulting from myocardial infarction. Also, the peptide can help to reduce the risk of heart attack and boost vascular health.

 

Potential Protective Benefits

Studies show that hexarelin can offer muscle protection through the regulation of calcium homeostasis. This can be very beneficial during cases of muscle ischemia, and traumatic muscle injury. In mouse models, Hexarelin also protects Skeletal muscle by inhibiting muscle wasting.

 

Hexarelin and Chemotherapy

Hexarelin protects different muscle tissues most especially during ischemic conditions. It has been considered as a potential adjunct for treating cancer. Although there is no vivid evidence of the direct effects of it on cancer cells, scientists are looking its protective action on muscle tissues against adverse effects of chemotherapy. The use of platinum-based drugs often leaves behind chemotherapeutic side effects. In the long-run, the activity of hexarelin in limiting muscle wasting can allow for the use of toxic drugs which can lead to the long-term survival of cancer patients

To learn more about this peptides, click here.